A complex and dangerous mix of substances is increasingly present in Calgary’s illicit drug supply, leading to a rise in overdose incidents this year. Researchers at the University of Calgary found that samples collected recently contained over 11 different substances, including potent opioids like fentanyl and carfentanil, methamphetamines, and tranquilizers. Monty Ghosh, a researcher involved in the study, described the variability in samples as problematic, complicating overdose resuscitation efforts. In 2025, the Calgary Drop-In Centre responded to approximately 1,300 overdoses, a figure that was surpassed by mid-April this year. The presence of veterinary-grade tranquilizers, such as medetomidine, has heightened concerns about the safety of the city’s drug supply, with outreach organizations reporting a significant increase in overdose cases.
Why It Matters
Calgary is experiencing a significant public health crisis as overdose cases rise sharply, nearly doubling in some instances compared to last year. Reports indicate that in the first four months of 2026, emergency medical services responded to 814 opioid-related events, highlighting the escalating nature of the crisis. The increase in complex overdoses is partly attributed to the emergence of highly toxic substances in the drug supply, including tranquilizers intended for animal use. This situation underscores the urgent need for effective intervention strategies and support systems to address the challenges posed by the ever-evolving illicit drug market.
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