Week 16 of the 2025/26 NFL season features a high-stakes NFC West showdown between the Los Angeles Rams and Seattle Seahawks, both holding an 11-3 record. The game, pivotal for division and playoff positioning, showcases Rams quarterback Matthew Stafford, a leading MVP candidate, against Seahawks quarterback Sam Darnold and a strong defense. Scheduled for December 18 at 8:15 p.m. ET at Lumen Field, the matchup will be broadcast on Amazon Prime Video. Betting odds favor the Seahawks by 1.5 points, with a predicted score of Rams 23, Seahawks 20.
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