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US engineers from Northwestern University have developed the world’s smallest pacemaker, measuring 1.8mm by 3.5mm by 1mm, which can be injected non-invasively into the body and controlled wirelessly via a wearable device. The device, designed for fragile hearts of newborns with congenital heart defects, offers a safer alternative for temporary pacing in patients with bradycardia and opens possibilities for bioelectronic medicines to help nerves and bones heal and block pain. This tiny bioresorbable pacemaker has been demonstrated to effectively pace human heart tissue and animal models, offering a minimally invasive treatment option with reduced overall risk.
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