The United States and Iran are resuming high-stakes negotiations in Rome regarding Tehran’s nuclear program, following constructive talks a week prior in Muscat. Iranian Foreign Minister Abbas Araghchi expressed cautious optimism about the U.S. side’s seriousness while asserting that Iran’s right to enrich uranium is non-negotiable. With the deadline for triggering the “snapback” mechanism on sanctions approaching, both sides face pressure to reach an agreement as Iran enriches uranium beyond the limits of the 2015 nuclear deal.