What is the weight-loss drug Orfoglipron and could it replace Ozempic?

Ukrainian firefighters battled a fire caused by mass Russian strikes in Donetsk on July 17, 2025, which resulted in three fatalities and 27 injuries. In the UK, German Chancellor Friedrich Merz emphasized the long-term threat posed by Putin to Europe, acknowledging the need for increased defense spending and collaboration among European nations in response to ongoing Russian aggression. Explain It To Me Like I'm 5: Ukrainian firefighters are working hard to put out fires caused...

Thunderstorms are expected across the UK today, with the Met Office issuing yellow weather warnings for heavy rain, lightning, and potential flash flooding, particularly in Durham, Middlesbrough, and Yorkshire. While southern regions may experience torrential rain and high temperatures reaching 30C, hosepipe bans are already in effect due to recent drought conditions. Explain It To Me Like I'm 5: Thunderstorms with heavy rain and warnings are expected across the UK this weekend, while some areas...

A British backpacker, Cameron James Wilkins, was assaulted by nine bar workers in Thailand after refusing to pay a £460 bill at the Diamond Karaoke Bar. The incident, captured on video, shows him being restrained and kicked by the staff, leading to police arrests and an investigation into the bar's practices of overcharging tourists. Explain It To Me Like I'm 5: A British tourist was attacked by bar workers in Thailand after he refused to...

Maria's treatment by Greater Manchester Police (GMP) was deemed "undefendable" by the chief constable following a high-profile inquiry that found her unlawful arrest and strip search unjustified. Despite this, a year later, she now faces a criminal conviction for the very offense the inquiry concluded she should never have been arrested for. Explain It To Me Like I'm 5: Maria was treated very unfairly by the police, and even though an investigation said she shouldn't...

A small plane, the Murphy SR3500 Moose, crashed in a remote area of Olympic National Park, Washington, on Tuesday, resulting in one death and two injuries. The National Transportation Safety Board is investigating the cause, while all victims were transported to a trauma center; the park remains a popular destination, attracting nearly 3 million visitors in 2023. Explain It To Me Like I'm 5: A small plane crashed in Olympic National Park, resulting in one...

Tensions escalated outside the Bell Hotel in Epping, Essex, where protests against a migrant housing situation turned chaotic, resulting in damage to police vehicles and confrontations with riot police. The protests were sparked by the presence of an Ethiopian man charged with multiple sexual assault offenses, prompting community leaders to criticize the appropriateness of housing vulnerable individuals in the area. Explain It To Me Like I'm 5: Protests at a hotel in Essex housing migrants...