Researchers from Duke-NUS Medical School and the National Neuroscience Institute in Singapore have discovered how gut microbes influence brain activity related to anxiety behaviors, suggesting probiotics could aid in mental health improvement. By studying germ-free mice, they found that the absence of gut microbes led to increased anxiety behaviors and heightened activity in the amygdala, a brain region associated with fear and anxiety. Introducing live microbes or indole compounds restored normal brain function and reduced anxiety, presenting new possibilities for targeted therapies in managing anxiety disorders.
Full Article






